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Angiogenesis

New data from P. Albers et al illuminate research in angiogenesis

Published in Gene Therapy Weekly, April 24th, 2008

According to a study from Kassel, Germany, "Treatment of localised renal cell carcinoma (RCC) is well established, and surgical resection is curative for most patients. However, for patients with either metastatic disease or whose local disease subsequently metastasises, treatment options have until recently been limited to cytokine therapy or chemotherapy, both of which are ineffective in the majority."

"As a result, prognosis has been poor for patients with metastatic RCC (mRCC). A better understanding of the pathogenesis of RCC has led to the development and application of therapies targeted at key molecules involved in angiogenesis, which is an integral part of...

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