Cancer Gene Therapy
Research from Tohoku University has provided new information about cancer gene therapy
Published in Gene Therapy Weekly, May 1st, 2008
"Low-intensity pulsed ultrasound (1 MHz; 1.3 W/cm(2)) and NBs were used to transduce the herpes simplex thymidine kinase (HSVtk) gene in vitro, leading to gene transfer. The addition of ganciclovir (GCV) to the transduced cells led to HSVtk/GCV-dependent cell death mediated by apoptosis. This technology was then assessed in vivo, using mice bearing subcutaneous tumors (1...
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Source: Gene Therapy Weekly (2008-05-01)
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