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Gene Therapy

Reports outline gene therapy study results from University of Tokyo, Medical Department

Published in Gene Therapy Weekly, May 1st, 2008

According to recent research from Hongo, Japan, "ERV-associated gastric carcinoma is a distinct subset of gastric carcinoma infected with EBV, which shows latency I type expression of EBV latent genes (EBNA1, EBER, BARF0, and LMP2A). To clarify the role of EBV in this type of gastric carcinoma, the cell biological characteristics (growth, apoptosis, and migration) were evaluated in gastric carcinoma cell lines (MKN-1, TMK1, MKN-74 and MKN-7) with and without infection of recombinant EBV harboring the neomycin resistance gene."

"The infection reiterated the latency I type infection, and the only difference observed in EBV-infected gastric carcinoma cell lines was the...

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