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Gene Therapy

Study results from Ohio State University broaden understanding of gene therapy

Published in Gene Therapy Weekly, May 15th, 2008

Data detailed in 'Effects of a topically applied bioadhesive berry gel on loss of heterozygosity indices in premalignant oral lesions' have been presented. According to recent research from the United States, "The aim of this study was to assess the effects of topical application of a 10% (w/w) freeze-dried black raspberry (FBR) gel on oral intraepithelial neoplasia (IEN) variables that included histologic diagnoses and loss of heterozygosity (LOH) indices. Microsatellite instability and/or LOH at tumor suppressor gene-associated chromosomal loci have been associated with a higher risk for oral IEN progression to oral squamous cell carcinoma."

"Previously, our...

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