Allergies
Data on allergies published by researchers at National Institute of Allergy and Infectious Diseases
Published in Gene Therapy Weekly, May 22nd, 2008
According to recent research published in the Journal of Biological Chemistry, "The temperature-dependent regulation of Shigella virulence genes is believed to be accomplished at the transcriptional stage by the regulators VirF and InvE. Several lines of evidence herein described indicate that post-transcriptional regulation of InvE expression plays a key role in the temperature-dependent regulation of virulence gene expression: (i) a considerable amount of invE mRNA continues to be transcribed under low temperature conditions, where the production of InvE protein is tightly repressed; (ii) the stability of invE mRNA markedly decreases, because its decay rate is significantly...
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Source: Gene Therapy Weekly (2008-05-22)
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