Life Sciences
McGill University, Department of Biomedical Engineering describes research in life sciences
Published in Gene Therapy Weekly, May 29th, 2008
Scientists discuss in 'Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors' new findings in life sciences. According to recent research published in the European Journal of Pharmaceutics and Biopharmaceutics, "It has been suggested that cell physiology may affect the internalization pathways of non-viral vectors, leading to cell line-dependent transfection efficiency. To verify this hypothesis, fluorescently labeled alginate-chitosan nanoparticle complexes were used as non-viral vectors to transfect 293T, COS7, and CHO cells and to observe the cellular interactions and internalization mechanisms of the...
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Source: Gene Therapy Weekly (2008-05-29)
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