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Gene Therapy Weekly

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DNA Research



Research conducted at University College has updated our knowledge about DNA research



May 29th, 2008

According to recent research published in the Journal of the American Chemical Society, "The intercalation of DNA into layered double hydroxides (LDHs) has various applications, including drug delivery for gene therapy and origins of life studies. The nanoscale dimensions of the interlayer region make the exact conformation of the intercalated DNA difficult to elucidate experimentally."

"We use molecular dynamics techniques, performed on high performance supercomputing grids, to carry out large-scale simulations of double stranded, linear and plasmid DNA up to 480 base pairs in length intercalated within a magnesium-aluminum LDH. Currently only limited...


Source: Gene Therapy Weekly (2008-05-29)

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