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Gene Therapy Weekly

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Gastric Cancer



Study findings on gastric cancer are outlined in reports from Washington University



May 29th, 2008

"We have characterized the adaptations of Helicobacter pylori to a rarely captured event in the evolution of its impact on host biology-the transition from chronic atrophic gastritis (ChAG) to gastric adenocarcinoma-and defined the impact of these adaptations on an intriguing but poorly characterized interaction between this bacterium and gastric epithelial stem cells. Bacterial isolates were obtained from a single human host colonized with a single dominant strain before and after his progression from ChAG to gastric adenocarcinoma during a 4-year interval," scientists in the United States report.

"Draft genome assemblies were generated from two isolates, one...


Source: Gene Therapy Weekly (2008-05-29)

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