Gene Therapy Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Gene Therapy
New research on gene therapy from Leiden University summarized
May 29th, 2008
According to recent research published in the journal Oncogene, "14-3-3 proteins are relevant to cancer biology as they are key regulators of major cellular processes such as proliferation, differentiation, senescence and apoptosis. So far, the sigma isoform (14-3-3 sigma) has most directly been implicated in carcinogenesis and was recognized as a tumour-suppressor gene." "The other six members of the mammalian 14-3-3 gene family likely behave as oncogenes, although direct evidence supporting this view is largely circumstantial. In this report, we show that knockdown of 14-3-3 zeta induces at least two isoform-specific phenotypes that are consistent with a...
Source: Gene Therapy Weekly (2008-05-29)
|
