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Gene Therapy
Recent studies from University of Texas add new data to gene therapy
May 29th, 2008
According to recent research published in the journal RNA - a Publication of the RNA Society, "Short double-stranded RNAs (dsRNA) are potent biological entities triggering a number of cellular effects. Most prominent among these is the post-transcriptional gene silencing of target genes by small interfering RNAs (siRNAs)." "In addition dsRNAs activate signal transduction processes through molecules like PKR or the Toll-like receptor important in viral defense and in explaining off target effects of siRNAs. Only a few of these dsRNA triggered pathways have been characterized yet. Here we show that the splicing variant D of the TAK1 gene is activated by short...
Source: Gene Therapy Weekly (2008-05-29)
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