Antisense Technology
Research results from H. Wang and colleagues update understanding of antisense technology
Published in Gene Therapy Weekly, June 19th, 2008
According to recent research published in the Journal of Cellular and Molecular Medicine, "The cardiac ankyrin repeat kinase (CARK) gene, also named TNNI3K for its interaction with cardiac troponin I, is both a unique expression and heart-enriched gene. To understand the mechanisms of CARK gene expression and regulation, we first cloned the full-length mRNA sequence and mapped the transcription start site of the mouse CARK gene and characterized its promoter regions."
"Two transcriptional isoforms of the CARK gene were identified in mouse heart tissue. Truncation analysis of the CARK promoter identified a minimal 151 bp region that has strong basal transcription...
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Source: Gene Therapy Weekly (2008-06-19)
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