Gene Therapy
Researchers at University College release new data on gene therapy
Published in Gene Therapy Weekly, July 3rd, 2008
"The unmodified TCR was poorly expressed in primary human T cells, suggesting that it competed inefficiently with endogenous TCR chains for cell surface expression. In order to improve this TCR, we replaced the human constant region with murine sequences, linked the two TCR genes using a self-cleaving 2A...
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Source: Gene Therapy Weekly (2008-07-03)
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