Gene Therapy

Researchers from Chungnam National University provide details of new studies and findings in the area of gene therapy

Published in Gene Therapy Weekly, July 3rd, 2008

"In a previous search for the differentially expressed genes in keratinocyte differentiation, we identified neutrophil gelatinise-associated lipocalin (NGAL) as a calcium-induced gene. In this study, we further verified the expression of NGAL in cultured keratinocytes as well as in several skin diseases," researchers in South Korea report.

"Reverse transcription-polymerase chain reaction (RT-PCR), Western blot, and ELISA clearly showed that NGAL expression was markedly increased in calcium-induced keratinocyte differentiation in vitro. However, in our previous report, NGAL expression was not detected in normal skin tissue except for hair follicle by in situ...

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Source: Gene Therapy Weekly (2008-07-03)

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