DNA Research
Researchers from Nanyang Technological University describe findings in DNA research
Published in Gene Therapy Weekly, July 17th, 2008
According to a study from Singapore, Singapore, "Controlled release studies of DNA from polymers have been limited, with most studies concentrating on microsphere formulations. This report details a study done on the release and transfection efficiencies of pDNA-lipofectamine complex (lipoplex), from selected polymeric films in which it was dispersed; the release and transfection efficiency was compared with that of naked pDNA."
"A biodegradable and a biostable polymer were compared. A sustained release profile was obtained from both the polymeric films. For the release of pDNA (naked DNA), a burst effect was always seen, and was suppressed using additives; for...
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Source: Gene Therapy Weekly (2008-07-17)
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