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Colon Cancer
Study data from N. Mourra et al provide new insights into colon cancer
July 17th, 2008
According to recent research published in the journal Diagnostic Molecular Pathology, "The prognosis of patients with colorectal cancer is largely determined by the tumor stage. In this respect, colorectal cancer with lymph node metastases has the worst prognosis." "Accordingly, there is considerable clinical interest in understanding the genetic mechanisms underlying metastasis formation. The short arm of chromosome 8 is often lost in colorectal cancer and has been associated with the advanced stages. A common region of deletion has been identified in 8p21, and we investigate here the localization of the putative tumor suppressor gene. A series of 683 sporadic...
Source: Gene Therapy Weekly (2008-07-17)
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