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Gene Therapy Weekly

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DNA Research



Investigators at University of Massachusetts release new data on DNA research



July 17th, 2008

According to a study from the United States, "Nonviral gene delivery technologies have been developed using layer-by-layer self-assembly of nanomaterials held together by electrostatic interactions in order to provide nanoparticulate materials that protect and delivery DNA to cells. Here we report a new DNA delivery technolog based on the in situ layer-by-layer synthesis of DNA nanoparticles caged within hollow yeast cell wall particles (YCWP)."

"YCWP provide protection and facilitate oral and systemic receptor-targeted delivery of DNA payloads to phagocytic cells. The nanoparticles inside YCWP consist of a core of tRNA/polyethylenimine (PEI) followed by a DNA layer...


Source: Gene Therapy Weekly (2008-07-17)

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