Gene Therapy Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Enzyme Research
University of Halle-Wittenberg reports research in enzyme research
July 17th, 2008
According to recent research published in the journal Leukemia, "The transcription factor C/EBP alpha (CEBPA) is a key player in granulopoiesis and leukemogenesis. We have previously reported the interaction of C/EBPa with other proteins ( utilizing mass spectrometry) in transcriptional regulation." "In the present study, we characterized the association of the MYST domain histone acetyltransferase Tat-interactive protein (TIP) 60 (HTA-TIP) with C/EBP alpha. We show in pull-down and co-precipitation experiments that C/EBP alpha and HTATIP interact. A chromatin immunoprecipitation (ChlP) and a confirmatory Re-ChlP assay revealed in vivo occupancy of the C/EBP...
Source: Gene Therapy Weekly (2008-07-17)
|
