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Gene Therapy Weekly

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Gene Therapy



New gene therapy study findings have been published by M. Obrien and colleagues



July 17th, 2008

"The regulatory mechanisms underlying myometrial smooth muscle contractility during labor are poorly understood. The authors therefore investigated the transcriptional profile of the charges that occur in the human myometrium at term pregnancy when compared with that at labor," researchers in Galway, Ireland report.

"Microarray technology was used to identify differentially expressed genes in human myometrium at labor. Real-time fluorescence reverse-transcriptase polymerase chain reaction (RT-PCR) was subsequently performed to verify the microarray data. Semiquantitative RT-PCR, Western blotting, and microscopy methodologies were also used. Certain novel genes were...


Source: Gene Therapy Weekly (2008-07-17)

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