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Gene Therapy
Research results from T. Ishikawa and colleagues update understanding of gene therapy
July 17th, 2008
According to a study from Moriguchi, Japan, "Menetrier's disease has been reported to be associated with Helicobacter pylori infection. The aim of this study was to investigate the genetic characteristics of various virulence factors and cytokine expression profiles in Helicobacter pylori isolated from patients with Menetrier's disease." "The genotyping of virulence factors was accomplished by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Induction of various cytokines in MKN45 cells or gastric fibroblasts by Helicobacter pylori stimulus was measured by real-time reverse transcription-PCR. We found that the Helicobacter pylori strain...
Source: Gene Therapy Weekly (2008-07-17)
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