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Gene Therapy Weekly

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Apoptosis



Studies from University of Minnesota have provided new information about apoptosis



July 17th, 2008

"The purpose of the current study was to determine spatiotemporal differences and to gain insight on the nisms responsible for lipid accumulation during apoptotic death using in vivo MR spectroscopic imaging in with histology and biochemical membrane lipid analyses. bearing BT4C gliomas were treated with ganciclovir (GCV) 14 days, and combined in vivo quantitative MR imaging (MRSI) of gliomas with histology and a analysis of major cell membrane constituents. By using MRSI in vivo in combination with histology, we were able demonstrate previously unattainable regional lipid concentration differences in tumors during GCV-induced apoptosis, 5-mu L tissue volume resolution," scientists writing...


Source: Gene Therapy Weekly (2008-07-17)

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