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Gene Therapy
Scientists at Indiana University, Medical Department target gene therapy
July 17th, 2008
"The T cell leukemia 3 (Tlx3) gene has been implicated in specification of glutamatergic sensory neurons in the spinal cord. In cranial sensory ganglia, Tlx3 is highly expressed in differentiating neurons during early embryogenesis," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report. "To study a role of Tlx3 during neural differentiation, mouse embryonic stem (ES) cells were transfected with a Tlx3 expression vector. ES cells stably expressing Tlx3 were grown in the presence or absence of a neural induction medium. In undifferentiated ES cells, there was no significant difference in gene...
Source: Gene Therapy Weekly (2008-07-17)
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