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Gene Therapy Weekly

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Gene Therapy



Studies from W.W. Hu and colleagues reveal new findings on gene therapy



July 17th, 2008

According to recent research published in the journal Cell Cycle, "The roles of the p53 protein in tumor suppression have been firmly established. However, the functions of this protein under normal conditions or in the absence of stress, if any, have remained a mystery."

"In humans, some alleles containing a functional single nucleotide polymorphism in the p53 gene and its negative regulator, the Mdm2 gene, are under positive selection over evolutionary time frames, suggesting that the p53 pathway might have important functions that are optimized and selected for by evolutionary or reproductive pressures. Indeed, a recent study demonstrated a new function for...


Source: Gene Therapy Weekly (2008-07-17)

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