Gene Therapy

Researchers from Fudan University provide details of new studies and findings in the area of gene therapy

Published in Gene Therapy Weekly, August 7th, 2008

According to a study from Shanghai, People's Republic of China, "A novel nonviral gene transfer vector was developed by modifying nanostructured lipid carrier (NLC) with cetylated polyethylenimine (PEI). Polycation nanostructured lipid carrier (PNLC) was prepared using the emulsion-solvent evaporation method."

"Its in vitro gene transfer properties were evaluated in the human lung adenocarcinoma cell line SPC-A1 and Chinese Hamster Ovary (CHO) cells. Enhanced transfection efficiency of PNLC was observed after the addition of triolein to the PNLC formulation and the transfection efficiency of the optimized PNLC was comparable to that of Lipofectamine (TM) 2000. In the...

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Source: Gene Therapy Weekly (2008-08-07)

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