Artificial Chromosomes
Investigators at Tottori University, Medical Department have published new data on artificial chromosomes
Published in Gene Therapy Weekly, August 7th, 2008
According to recent research published in the Journal of Human Genetics, "Gene therapy using cDNA driven by an exogenous promoter is not suited for genetic disorders that require intrinsic expression of a transgene, such as hyperimmunoglobulin (Ig)M syndrome (HIGM), which is caused by mutations in the CD40L gene. The human artificial chromosome (HAC) vector has the potential to solve this problem, because it can be used to transfer large genomic fragments containing their own regulatory elements."
"In this study, we examined whether introduction of a genomic fragment of CD40L via the HAC vector permits intrinsic expression of the transgene and has an effect on...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2008-08-07)
More Articles from Gene Therapy Weekly
- Emory University
Class of antibiotics can enhance gene-silencing tool - Angiogenesis
Research on angiogenesis described by scientists at University of Helsinki - Antibody Engineering
Intravenous Gammaglobulin (IVIG) plus Rituximab Improves Chances for Successful Transplantation in High Immunologic-Risk Patients - Applied Biosystems Inc.
Scientists Report Most Comprehensive View of Mammalian Transcriptome - Atherosclerosis
Study findings from Kanazawa University provide new insights into atherosclerosis - Brain Cancer
Researchers from University of Texas, Brain Tumor Center detail findings in brain cancer - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
