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Data on life sciences reported by researchers at Emory University, Department of Medicine

Published in Gene Therapy Weekly, August 7th, 2008

Fresh data on life sciences are presented in the report 'Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells.' "The proliferation of vascular smooth muscle cells is important in the pathogenesis of many vascular diseases. Reactive oxygen species (ROS) produced by NADPH oxidases in smooth muscle cells have been shown to participate in signaling cascades regulating proliferation induced by platelet-derived growth factor (PDGF), a powerful smooth muscle mitogen," researchers in the United States report.

"We sought to determine the role of Nox5 in the regulation of PDGF-stimulated human aortic smooth muscle cell (HASMC) proliferation. Cultured HASMC...

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