Osteosarcoma Gene Therapy
Baylor College of Medicine, College of Medicine describes research in osteosarcoma gene therapy
Published in Gene Therapy Weekly, August 14th, 2008
Data detailed in 'Cell cycle regulator gene CDC5L, a potential target for 6p12-p21 amplicon in osteosarcoma' have been presented. According to recent research from the United States, "Osteosarcoma is a primary malignant tumor of bone arising from primitive bone-forming mesenchymal cells and accounts for approximately 60% of malignant bone tumors. Our comparative genomic hybridization (CGH) studies have identified frequent amplification at 6p12-p21, 12q13-q15, and 17p11.2 in osteosarcoma."
"Of these amplified regions, 6p12-p21 is particularly interesting because of its association with progression and poor prognosis in patients with osteosarcoma. In an attempt to...
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Source: Gene Therapy Weekly (2008-08-14)
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