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Enzyme Research
Research results from S. Tanaka and colleagues update understanding of enzyme research
August 14th, 2008
"A new adjuvant therapy, individual adjuvant therapy (IAT), which is individualized according to the results of real-time reverse-transcription polymerase chain-reaction (RT-PCR) for O-6-methylguanine-DNA methyltransferase (MGMT), was used to treat malignant gliomas. Immediately after the operation, mRNA expression for drug-resistance genes was investigated in frozen samples of malignant gliomas from 55 patients (30 glioblastoma multiformes, 20 anaplastic astrocytomas and 5 anaplastic oligodendroglial tumors) by real-time quantitative RT-PCR with specific primers for MGMT," scientists in Ibaraki, Japan report. "Forty-two patients were treated with...
Source: Gene Therapy Weekly (2008-08-14)
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