Gene Therapy Weekly
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Gene Therapy
Investigators at University of California target gene therapy
August 14th, 2008
According to recent research from the United States, "The dynamic features of a genetic network's response to environmental fluctuations represent essential functional specifications and thus may constrain the possible choices of network architecture and kinetic parameters. To explore the connection between dynamics and network design, we have analyzed a general regulatory architecture that is commonly found in many metabolic pathways." "Such architecture is characterized by a dual control mechanism, with end product feedback inhibition and transcriptional regulation mediated by an intermediate metabolite. As a case study, we measured with high temporal resolution the...
Source: Gene Therapy Weekly (2008-08-14)
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