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Gene Therapy
New gene therapy research from University of Lausanne outlined
August 14th, 2008
According to recent research from Lausanne, Switzerland, "Genomic islands, large potentially mobile regions of bacterial chromosomes, are a major contributor to bacteria evolution. Here, we investigated the fitness cost and phenotypic differences between the bacterium Pseudomonas aeruginosa PAO1 and a derivative carrying one integrated copy of the clc element, a 103-kb genomic island [and integrative and conjugative element (ICE)] originating in Pseudomonas sp. strain B13 and a close relative of genomic islands found in clinical and environmental isolates of A aeruginosa." "By using a combination of whole genome transcriptome profiling, phenotypic arrays, competition...
Source: Gene Therapy Weekly (2008-08-14)
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