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Gene Therapy Weekly

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Gene Therapy



Research by Y.L. Han and colleagues in gene therapy provides new insights



August 14th, 2008

According to recent research from Shenyang, People's Republic of China, "This study examined the effect on neointimal hyperplasia of adenovirus-mediated delivery of cellular repressor of EIA-stimulated genes (CREG) to the artery after balloon injury. Sixty rabbits were randomized into three groups and underwent balloon injury in the left common carotid arteries."

"The injured arterial segment was isolated by two inflated balloon catheters. Saline or recombinant adenovirus expressing CREG or green fluorescent protein was injected into the lumen of the isolated arterial segments and incubated for 30 minutes. The rabbits were euthanized for immunohistochemistry, Western...


Source: Gene Therapy Weekly (2008-08-14)

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