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Angiogenesis
Research conducted at M.A. Engelse and co-authors has provided new information about angiogenesis
August 14th, 2008
"The formation of new tubular structures from a quiescent endothelial lining is one of the hallmarks of sprouting angiogenesis. This process can be mimicked in vitro by inducing capillary-like tubular structures in a three-dimensional (3D) fibrin matrix," scientists writing in the journal Angiogenesis report. "We aimed to analyze the differential mRNA expression in two phenotypically distinct cell populations from the same culture, namely in tubule-forming endothelial cells and monolayer endothelial cells not participating in tubule formation. A fibrin-rich 3D matrix derived from human plasma was used to facilitate tubule formation by human foreskin microvascular...
Source: Gene Therapy Weekly (2008-08-14)
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