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Gene Therapy Weekly

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Life Sciences



Data on life sciences detailed by C. Sinoquet and co-authors



August 14th, 2008

According to recent research published in the journal Nucleic Acids Research, "This article compares 32 bacterial genomes with respect to their high transcription potentialities. The 70 promoter has been widely studied for Escherichia coli model and a consensus is known."

"Since transcriptional regulations are known to compensate for promoter weakness (i.e. when the promoter similarity with regard to the consensus is rather low), predicting functional promoters is a hard task. Instead, the research work presented here comes within the scope of investigating potentially high ORF expression, in relation with three criteria: (i) high similarity to the 70 consensus...


Source: Gene Therapy Weekly (2008-08-14)

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