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Gene Therapy Weekly

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Apoptosis



Studies from B.D. Cosgrove and co-authors have provided new information about apoptosis



August 14th, 2008

"Tumor necrosis Factor-alpha (TNF) is an inflammatory cytokine that induces context-dependent proliferation, survival, and apoptosis responses in hepatocytes. TNF stimulates and enhances growth factor-mediated hepatocyte proliferation and survival Wowing partial hepatectomy, but also acts in concert with other inflammatory cytokines of the innate immune response during viral infection to induce apoptosis in hepatocytes," scientists in the United States report.

"In other epithelial cell types, TNF has recently been shown to stimulate autocrine release of transforming growth factor-alpha (TGF-alpha) and interleukin-1 (IL-1) family ligands. Here, we examine the role of...


Source: Gene Therapy Weekly (2008-08-14)

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