Published in Gene Therapy Weekly, August 21st, 2008
"The BACE1-antisense transcript (BACE1-AS) regulates BACE1 mRNA and subsequently BACE1 protein expression in vitro and in vivo. Upon exposure to various cell stressors including amyloid-beta 1-42 (A beta 1-42), expression of BACE1-AS becomes elevated, increasing BACE1 mRNA stability and generating...
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