Breast Cancer

New breast cancer study findings have been reported by scientists at Genentech, Inc.

Published in Gene Therapy Weekly, August 21st, 2008

"Breast cancer is a heterogeneous disease with distinct molecular subtypes characterized by differential response to targeted and chemotherapeutic agents. Enhanced understanding of the genetic alterations characteristic of different subtypes is needed to pave the way for more personalized administration of therapeutic agents," scientists in the United States report.

"We have taken a functional genomics approach using a well-characterized panel of breast cancer cell lines to identify putative biomarkers of resistance to antimitotic agents such as paclitaxel and monomethyl-auristatin-E (MMAE). In vitro studies revealed a striking difference in sensitivity to these agents...

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Source: Gene Therapy Weekly (2008-08-21)

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