Published in Gene Therapy Weekly, August 21st, 2008
"Here, we report a comprehensive investigation of the regulatory mechanism of a heat-induced gene (hsp5) from Halobacterium salinarum. We demonstrated by mutation analysis that the sequences 5' and 3' to the core elements (TATA box and BRE) of the hsp5 promoter (P-hsp5) did not significantly affect the basal and heat-induced gene expression, as...
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