Gene Therapy
Researchers at University of Illinois target gene therapy
Published in Gene Therapy Weekly, August 28th, 2008
Researchers detail in 'FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness,' new data in gene therapy. According to recent research published in the Journal of Biological Chemistry, "The Forkhead box M1 (FoxM1) protein is a proliferation-specific transcription factor that plays a key role in controlling both the G(1)/S and G(2)/M transitions through the cell cycle and is essential for the development of various cancers. We show here that FoxM1 directly activates the transcription of the c-Jun N-terminal kinase (JNK1) gene in U2OS osteosarcoma cells."
"Expression of JNK1, which regulates the expression of genes...
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Source: Gene Therapy Weekly (2008-08-28)
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