Cord Blood
Researchers from Sydney Children's Hospital report details of new studies and findings in the area of cord blood
Published in Gene Therapy Weekly, August 28th, 2008
"Here we show that GSK-3 beta inhibition activates beta-catenin in cord blood CD34(+) cells and upregulates beta-catenin transcriptional targets c-myc and HoxB4, both known to regulate HSC self-renewal. GSK-3 beta inhibition resulted in delayed ex vivo expansion of CD34(+) cells, yet enhanced the preservation of stem cell activity as tested in long-term culture with bone...
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Source: Gene Therapy Weekly (2008-08-28)
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