Published in Gene Therapy Weekly, September 11th, 2008
"We cloned HRASLS2 cDNA from human SW480 colon cancer cells. Most wild-type, and some N- and C-terminal truncated HRASLS2 (HRASLS2 Delta N Delta C) were expressed as a granular pattern located at perinuclear region in HtTA cervical cancer cells, while truncation at the C-terminus only (HRASLS2 Delta C) resulted in a diffuse pattern. Wild-type HRASLS2 significantly suppressed colony formation of...
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