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Gene Therapy

Data on gene therapy described by researchers at Dartmouth University, Department of Biochemistry

Published in Gene Therapy Weekly, September 18th, 2008

Researchers detail in 'Synthetic genetic array analysis in Saccharomyces cerevisiae provides evidence for an interaction between RAT8/DBP5 and genes encoding P-body components,' new data in gene therapy. "Coordination of the multiple steps of mRNA biogenesis helps to ensure proper regulation of gene expression. The Saccharomyces cerevisiae DEAD-box protein Rat8p/Dbp5p is an essential mRNA export factor that functions at the nuclear pore complex (NPC) where it is thought to remodel mRNA/protein complexes during mRNA export," investigators in the United States report.

"Rat8p also functions in translation termination and has been implicated in functioning during...

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