Plague

Recent findings in plague described by L. Vitagliano and colleagues

Published in Gene Therapy Weekly, October 2nd, 2008

According to a study from Naples, Italy, "Bacterial infectivity often relies on efficient attachment to the host cells through adhesive extensions. Unveiling the structural basis of the formation of these organelles is of paramount importance for both academic and applicative implications."

"Computational approaches may fruitfully complement experimental studies by providing information on specific conformational states whose characterization is difficult. Here, we report molecular dynamics characterizations of Yersinia pestis Caf1 subunit in its monomeric-unbound and dimeric states. Data on the monomeric form indicate that it is highly reactive and evolves toward...

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Source: Gene Therapy Weekly (2008-10-02)

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