World Journal of Gastroenterology
A prospective clinical diagnosis marker for digestive system cancer: nm23H1
Published in Gene Therapy Weekly, October 9th, 2008
Growing evidence suggests that accumulation of multiple alterations such as activation of proto-oncogenes and inactivation of tumor suppressor genes is responsible for the development and progression of digestive system cancer. Genetic instability of oncogenes such as microsatellite instability (MSI) and loss of heterozygosity (LOH) is probably associated with mutations in genes responsible for tumor-genesis, and they play important roles in tumor clinical pathology. The studies of MSI and LOH of digestive system cancer have been focused on genetic instability of P53, P16 and FHIT, but few studies were seen in gene nm23H1.
A research article to be published on September...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2008-10-09)
More Articles from Gene Therapy Weekly
- World Journal of Gastroenterology
How does the microsatellite alterate in metaplasia-dysplasia-adenocarcinoma sequence? - World Journal of Gastroenterology
LOH analysis on 4q in sporadic colorectal carcinoma - Allergies
Study data from National Institute of Allergy and Infectious Diseases update understanding of allergies - Apoptosis
New apoptosis research from Chung-Ang University outlined - Bone Marrow
Research results from S. Derdouch and co-authors update knowledge of bone marrow - Breast Cancer
Research conducted at J. Veeck and co-researchers has updated our knowledge about breast cancer - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
