Published in Gene Therapy Weekly, October 9th, 2008
"In this study, we demonstrate that p19(ras) interaction with p73 beta amplifies p73 beta-induced apoptotic signaling responses including Bax mitochondrial translocation, cytochrome c release, increased production of reactive oxygen species (ROS) and loss of mitochondrial transmembrane potential (Delta psi(m)). Furthermore, endogenous expression of p19(ras) and p73...
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