RNA Research

Recent findings from Yale University highlight research in RNA research

Published in Gene Therapy Weekly, October 16th, 2008

"West Nile virus ( WNV), and related flaviviruses such as tick- borne encephalitis, Japanese encephalitis, yellow fever and dengue viruses, constitute a significant global human health problem(1). However, our understanding of the molecular interaction of such flaviviruses with mammalian host cells is limited(1)," researchers in the United States report.

"WNV encodes only 10 proteins, implying that it may use many cellular proteins for infection(1). WNV enters the cytoplasm through pH- dependent endocytosis, undergoes cycles of translation and replication, assembles progeny virions in association with endoplasmic reticulum, and exits along the secretory pathway(1-3)....

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Source: Gene Therapy Weekly (2008-10-16)

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