Gene Therapy

Reports from University of Rochester add new data to research in gene therapy

Published in Gene Therapy Weekly, October 16th, 2008

"Estrogen receptor a (ER alpha) has been reported to be expressed and function in the prostate stromal cells, and numerous evidences indicated that the stromal ER alpha signal pathway plays critical roles in prostate development and cancer. ER alpha requires distinct coregulators for efficient transcriptional regulation," researchers in the United States report.

"The goal of this study is to examine physical and functional interaction between ER alpha and ERAP75 in the context of prostate stromal cells. Yeast two-hybrid assays were used to screen novel ER alpha interaction proteins. The interaction between ER alpha and ERAP75 was confirmed by mammalian two-hybrid, GST...

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Source: Gene Therapy Weekly (2008-10-16)

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