Gene Therapy
Reports outline gene therapy study findings from University Hospital
Published in Gene Therapy Weekly, October 16th, 2008
New research, 'Intracrine signalling of activin A in hepatocytes upregulates connective tissue growth factor (CTGF/CCN2) expression,' is the subject of a report. "Up to now, the effect of activin A on the expression of the important transforming growth factor (TGF)-beta downstream modulator connective tissue growth factor (CTGF) is not known, but might be of relevance for the functional effects of this cytokine on several liver cell types. In this study, activin A-dependent CTGF expression in hepatocytes (PC) primed by exogenous activin A and in PC maintained under complete activin-free culture conditions was analysed by Western blots, metabolic labelling, gene silencing, reverse...
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Source: Gene Therapy Weekly (2008-10-16)
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