Published in Gene Therapy Weekly, October 23rd, 2008
"The AR has been considered as a critical determinant for the development and progression of human prostate cancers. In this study, we sought to identify the PI3K isoforms involved in AR transactivation. Using a gene-specific small interference RNA (siRNA) approach, we determined that the regulatory isoform p85 alpha and the catalytic isoform p110 beta, but not p110 alpha, were...
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