Published in Gene Therapy Weekly, October 23rd, 2008
"We examined the three members of the DNA methyltransferase (DNMT) enzyme family in normal and neoplastic human and mouse pituitary cells. This study was performed at a university-affiliated cancer research institute. Gene expression, promoter DNA methylation, histone modifications, and cell proliferation were determined. In contrast to DNMT1 and DNMT3a, DNMT3b was expressed at relatively higher levels in neoplastic pituitary cells. However,...
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