Gene Therapy

Research from Tel-Aviv University has provided new data on gene therapy

Published in Gene Therapy Weekly, October 23rd, 2008

"Direct in vivo investigation of mammalian metabolism is complicated by the distinct metabolic functions of different tissues. We present a computational method that successfully describes the tissue specificity of human metabolism on a large scale," investigators in Tel Aviv, Israel report.

"By integrating tissue-specific gene- and protein-expression data with an existing comprehensive reconstruction of the global human metabolic network, we predict tissue-specific metabolic activity in ten human tissues. This reveals a central role for post- transcriptional regulation in shaping tissue-specific metabolic activity profiles. The predicted tissue specificity of genes...

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Source: Gene Therapy Weekly (2008-10-23)

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