Adrenocortical Cancer

Studies in the area of adrenocortical cancer reported from University of California

Published in Gene Therapy Weekly, October 30th, 2008

"The gene expression profiles of benign and malignant adrenocortical tumors are different. Genomewide gene expression profiling and validation," researchers in the United States report.

"Tertiary medical center. Eighty-five patients with benign adrenocortical tumors (n = 74) and adrenocortical carcinoma (n = 11). Real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR) in 89 adrenocortical tissue samples (11 malignant and 78 benign). The criteria for differentially expressed genes between benign and malignant adrenocortical tumors were a false discovery rate of less than 5% and an adjusted P< .01. Genes differentially expressed by 8-fold higher...

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Source: Gene Therapy Weekly (2008-10-30)

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